A simplified model for mitochondrial ATP production

A simplified model for mitochondrial ATP production.

Most of the adenosine triphosphate (ATP) synthesized during glucose metabolism is produced in the mitochondria through oxidative phosphorylation. This is a complex reaction powered by the proton gradient across the mitochondrial inner membrane, which is generated by mitochondrial respiration. A detailed model of this reaction, which includes dynamic equations for the key mitochondrial variables...

Regulation of ATP production by mitochondrial Ca2+

Stimulation of mitochondrial oxidative metabolism by Ca(2+) is now generally recognised as important for the control of cellular ATP homeostasis. Here, we review the mechanisms through which Ca(2+) regulates mitochondrial ATP synthesis. We focus on cardiac myocytes and pancreatic β-cells, where tight control of this process is likely to play an important role in the response to rapid changes in...

Mitochondrial acetate and ATP production in trypanosomes

a Simplified Model of Distributed Parameter Systems

A generalized simplified model for describing the dynamic behavior of distributed parameter systems is proposed. The various specific characteristics of gain and phase angle of distributed parameter systems are investigated from frequency response formulation and complex plane representation of the proposed simplified model. The complex plane investigation renders some important inequality cons...

Animation model to conceptualize ATP generation: a mitochondrial oxidative phosphorylation

Adenosine triphosphate (ATP) is the molecular unit of intracellular energy and it is the product of oxidative phosphorylation of cellular respiration uses in cellular processes. The study explores the growth of the misconception levels amongst the learners and evaluates the effectiveness of animation model over traditional methods. The data obtained from the sixty B...